Frequently Asked Questions

Answers to common questions about ion-selective electrode measurements, maintenance, calibration, and troubleshooting. Based on over 25 years of customer support experience.

All (19)Basics (4)Sample Preparation (1)Measurement Quality (4)Equipment Setup (1)Maintenance (3)Troubleshooting (2)Measurement (3)Calibration (1)

Basics

Sample Preparation

Measurement Quality

Equipment Setup

Maintenance

Troubleshooting

Measurement

Calibration

Related Resources

Beginner's Guide

Comprehensive introduction to ISE theory and practice — the award-winning guide used by researchers worldwide.

Read the guide

Understanding ISAB & Activity

Deep dive into ionic activity, activity coefficients, and when to use ionic strength adjustment buffers.

Dealing with Interference

Understanding selectivity coefficients and practical strategies for minimising ionic interference in your measurements.

Can't find your answer?

Our technical team is happy to answer any questions about electrode selection, calibration methods, or troubleshooting your specific application.

Read the Guide

Frequently Asked Questions

Basics

What do Ion-Selective Electrodes measure?

What is the difference between activity and concentration?

What is the shelf life and operating life of an ISE?

Does the operating life of an ISE depend on the number of samples analysed?

Sample Preparation

What is ISAB and when is it used?

Measurement Quality

What is meant by interference in ISE measurements?

What precision can I expect from an ISE measurement?

What is meant by 'drift' in ISE measurements?

What is the effect of temperature change on ISE measurements?

Equipment Setup

How do I choose the correct reference electrode?

Maintenance

Do I need to replace or top-up any electrode filling solutions?

How do I clean contaminated membranes?

How should I store the electrodes between analytical sessions?

Troubleshooting

What can I do about a noisy electrode signal?

What should I do if the measured electrode slope is outside the specified limits?

Measurement

After immersing the electrodes, how long should I wait before taking a reading?

What is the concentration range and detection limit for an ISE measurement?

What range of milliVolt readings can I expect from my ISE?